1 - Maxillofacial Trauma

Summary

text Maxillofacial Anatomy and Trauma Review

TopicCategoryKey Details
Maxillofacial AnatomyBonesMaxilla (upper jaw) and Mandible (only movable bone).
Maxillofacial AnatomyMusclesMuscles of Mastication are supplied by CN V3 and include the Masseter, Temporalis, Medial Pterygoid, and Lateral Pterygoid.
Maxillofacial AnatomyMusclesThe Lateral Pterygoid muscle is responsible for opening the mouth (Mnemonic: LO - Lateral Opens).
Maxillofacial AnatomyNerve BranchesFacial Nerve (CN VII) branches are the Temporal, Zygomatic, Buccal, Mandibular, and Cervical (Mnemonic: "To Zanzibar By Motor Car").
Maxillofacial AnatomySensory SupplyTrigeminal Nerve (CN V1) - Ophthalmic supplies the forehead, upper eyelid, and dorsum of the nose.
Maxillofacial AnatomySensory SupplyTrigeminal Nerve (CN V2) - Maxillary supplies the lower eyelid, upper lip, and maxillary teeth.
Maxillofacial AnatomySensory SupplyTrigeminal Nerve (CN V3) - Mandibular supplies the lower lip, chin, and mandibular teeth.
Maxillofacial AnatomyBlood SupplyExternal Carotid Artery (ECA) has 8 branches: 1. Superior Thyroid, 2. Ascending Pharyngeal, 3. Lingual, 4. Facial, 5. Occipital, 6. Posterior Auricular, 7. Maxillary, 8. Superficial Temporal (Mnemonic: "Seven Angry Ladies Fight Over PMS").
Maxillofacial AnatomyVenousDanger Triangle of the face involves the facial vein draining to the ophthalmic vein then to the cavernous sinus, allowing infections to spread to the brain.
Maxillofacial AnatomyLymphaticsSubmental lymph nodes drain the chin, lower lip, and floor of the mouth.
Maxillofacial AnatomyLymphaticsSubmandibular lymph nodes drain the medial face, nose, and upper lip.
Maxillofacial AnatomyForaminaMandibular foramen is the entry point for the Inferior Alveolar Nerve (V3).
TopicCategoryKey Details
Initial AssessmentPrioritiesPriorities of management follow: 1. Circulation/hemorrhage, 2. Airway, 3. Shock, 4. Life-threatening associated injuries, 5. Local injuries, 6. Triage.
Initial AssessmentShockSigns of shock include early hypertension followed by hypotension, increased heart rate, blurring of vision, syncope, and loss of consciousness.
Initial AssessmentAirwayCauses of airway problems include the tongue falling back, dentures/blood clots/aspiration, direct laryngeal trauma, and multiple facial fractures.
Airway ManagementProceduresEndotracheal Intubation is the fastest general procedure to secure an airway but is contraindicated by tumors or fractured mandibles where the tongue cannot be elevated.
Airway ManagementProceduresCricothyrotomy is a temporary first-aid/emergency airway performed at the cricothyroid ligament; it is the "fastest" in a field/barrio setting to prevent hypoxic encephalopathy.
Airway ManagementProceduresTracheostomy is the preferred definitive airway in a hospital setup and can be performed quickly (4 mins) in patients with tetanus (risus sardonicus) where ETT is impossible.
TopicCategoryKey Details
Nasal Bone TraumaFeaturesNasal bone fractures are the MOST frequently traumatized bones in the face due to their prominence.
Nasal Bone TraumaSignsSigns of nasal fracture include septal deviation, epistaxis, nasal obstruction, and crepitation.
Nasal Bone TraumaClassificationPlane 3 Nasal Injury according to Stranc and Robertson involves a naso-orbitoethmoidal (NOE) fracture and the orbit.
Nasal Bone TraumaTreatmentClosed Reduction is the gold standard for nasal bone fractures if performed within 2 weeks of injury.
Nasal Bone TraumaTreatmentOpen Reduction and Internal Fixation (ORIF) with titanium implants is required for nasal fractures >2 weeks old due to callus formation.
Nasal Bone TraumaFirst AidNasal packing serves to control bleeding and can temporarily elevate fractured bone, but must be removed within 24-48 hours to avoid SSI/Staphylococcal infection.
TopicCategoryKey Details
Mandible TraumaFeaturesMandibular fractures are the 2nd most common facial fractures and the most common case encountered by interns.
Mandible TraumaAnatomyMandible parts include: Symphysis (midline), Parasymphysis (midline to canine), Body (canine to 3rd molar), Angle, Ramus, Coronoid, Condyle, and Alveolus.
Mandible TraumaNerve InjuryMandibular body fractures are specifically associated with paresthesia of the lower jaw and numbness of the lower lip due to V3 (Inferior Alveolar Nerve) compression.
Mandible TraumaClassificationFavorable mandibular fractures are those where muscle forces (Masseter) tend to keep bone fragments together.
Mandible TraumaClassificationUnfavorable mandibular fractures occur when muscle pull separates the bone fragments, necessitating ORIF.
Mandible TraumaHallmark SignSublingual hematoma is the most important sign to recognize in mandibular trauma as it indicates a pending upper airway obstruction.
Mandible TraumaSignsTrismus is defined as an inter-incisor distance of less than 1.5 cm (normal is ~3 cm or 3 finger breadths).
Mandible TraumaSignsMalocclusion is an abnormal bite; it is a clinical diagnosis where the patient cannot bite "normally."
Mandible TraumaSignsOtorrhagia can occur if a fractured mandibular condyle pierces the external auditory canal.
Mandible TraumaDiagnosticsTowne’s view X-ray is specifically used to check the mandibular Condyle.
Mandible TraumaDiagnosticsPanoramic X-ray is used to evaluate the Mandibular Body.
Mandible TraumaTreatmentErich Braces (Dental Arch Bars) are used for closed reduction in favorable fractures to lock the bite for 3-4 weeks.
Mandible TraumaTreatmentRestoring occlusion (normal bite) is the most important goal in managing mandibular fractures.
TopicCategoryKey Details
Maxillary TraumaClassificationLeFort I (Guerin fracture) is a horizontal fracture of the palate/maxilla.
Maxillary TraumaClassificationLeFort II (Pyramidal fracture) separates the midface from the cheeks, passing through nasal and zygomaticomaxillary sutures.
Maxillary TraumaClassificationLeFort III (Craniofacial dysjunction) separates the midface from the upper face/cranium.
Maxillary TraumaDiagnostic SignDrawer’s sign is performed by pulling the dentition while stabilizing the face to check for movement at different LeFort levels.
Maxillary TraumaManagementNasogastric Tube (NGT) insertion is dangerous in LeFort III fractures because the tube may inadvertently enter the brain.
TopicCategoryKey Details
Zygoma TraumaFeaturesZygomaticomaxillary Complex (ZMC) Fracture (formerly Tripod fracture) involves 6 structures including the zygomaticofrontal, maxillary, temporal, and sphenoid sutures.
Zygoma TraumaDiagnosticsTeardrop sign on Water’s view X-ray indicates orbital contents (fat/muscle) herniating into the maxillary sinus.
Zygoma TraumaSignsLimitation of eye motion and diplopia are the most critical functional findings in ZMC fractures.
Zygoma TraumaMuscleInferior oblique muscle is the most common muscle entrapped in ZMC/orbital fractures, limiting upward/lateral gaze.
Zygoma TraumaNerve InjuryInfraorbital nerve (V2) injury in ZMC fractures causes numbness of the lateral nose, upper lip, and cheek.
Zygoma TraumaSignsHypoglobus is the inferior displacement of the orbit, while Enophthalmos is the posterior displacement.
Zygoma TraumaTreatmentIndications for ORIF in ZMC are functional: 1. Limitation of eye motion, 2. Diplopia, 3. Trismus.
Zygoma TraumaDiagnosticsForced Duction Test is used to differentiate muscle entrapment (eye won't move) from nerve paralysis (eye moves when grasped).

Differentiating Similar Entities for Exams:

  1. Nasal Bone vs. Mandible: The Nasal Bone is the #1 most common facial fracture; Mandible is the #2 most common.
  2. Cricothyrotomy vs. Tracheostomy: Cricothyrotomy is a temporary emergency first-aid; Tracheostomy is the definitive hospital-based airway.
  3. V2 vs. V3 Nerve Injury: V2 (Maxillary) injury causes upper lip/cheek numbness (common in ZMC/Maxilla fractures); V3 (Mandibular) injury causes lower lip/chin numbness (common in Mandibular body fractures).
  4. Favorable vs. Unfavorable Mandible Fracture: Favorable fractures are held together by muscle pull; Unfavorable fractures are pulled apart and require surgery (ORIF).
  5. LeFort I vs. II vs. III: LeFort I is the palate only; LeFort II is the pyramidal/midface; LeFort III is the entire face separating from the skull.
  6. Trismus (Mandible) vs. Trismus (ZMC): In Mandible fractures, trismus is due to pain/displacement; in ZMC fractures, it is often due to the zygomatic arch impinging on the Coronoid Process.
  7. Hypoglobus vs. Enophthalmos: Hypoglobus is an "up/down" displacement (downward); Enophthalmos is a "front/back" displacement (sunken eyes).
  8. Manual reduction vs. ORIF timing: Nasal fractures should be closed-reduced within <2 weeks; after 2 weeks, they require Open Reduction (ORIF).
  9. Forced Duction Test Results: If the eye is restricted/cannot be moved manually, it is muscle entrapment; if the eye moves easily manually but not on its own, it is nerve paralysis.
  10. Submental vs. Submandibular Drainage: Submental drains the chin/floor of mouth; Submandibular drains the medial face/upper lip.
  11. Lateral Pterygoid vs. Other Masticatory Muscles: Lateral Pterygoid "Opens" the mouth; Masseter, Temporalis, and Medial Pterygoid "Close" the mouth.
  12. Towne’s View vs. Panoramic X-Ray: Towne’s is best for the Condyle; Panoramic (Panorex) is best for the Mandibular Body.
  13. Water’s View vs. Other X-rays: Water’s view is the specific X-ray used to see the Teardrop sign in orbital/ZMC fractures.
  14. Functional vs. Cosmetic Indications: In ZMC fractures, diplopia and trismus (functional) are primary indicators for surgery, while enophthalmos (cosmetic) is secondary.
  15. Cricothyrotomy Tube vs. Method: Cricothyrotomy is performed between the thyroid and cricoid cartilages; Tracheostomy is performed lower in the neck (tracheal rings).

QA

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MAXILLOFACIAL ANATOMY

  1. Name the two primary bones involved in Maxillofacial Anatomy. | Maxilla and Mandible.
    Maxilla is the upper jaw; Mandible is the lower jaw.
  2. Which bone is the only movable bone in the maxillofacial region? | Mandible.
  3. Which nerve supplies the Muscles of Mastication? | Trigeminal Nerve (CN V3).
  4. List the four (4) Muscles of Mastication. | 1) Masseter
    2) Temporalis
    3) Medial Pterygoid
    4) Lateral Pterygoid
  5. Which specific muscle is responsible for opening the mouth? | Lateral Pterygoid.
    Mnemonic: LO - Lateral Opens.
  6. What are the five (5) branches of the Facial Nerve (CN VII)? | 1) Temporal
    2) Zygomatic
    3) Buccal
    4) Mandibular
    5) Cervical
  7. State the mnemonic for the Facial Nerve (CN VII) branches. | "To Zanzibar By Motor Car".
  8. What area is supplied by the Trigeminal Nerve (CN V1) - Ophthalmic? | Forehead, upper eyelid, nose.
    Supplies the dorsum of the nose.
  9. What area is supplied by the Trigeminal Nerve (CN V2) - Maxillary? | Lower eyelid and cheek.
    Supplies upper lip and maxillary teeth.
  10. What area is supplied by the Trigeminal Nerve (CN V3) - Mandibular? | Lower lip and chin.
    Supplies the mandibular teeth.
  11. How many branches does the External Carotid Artery (ECA) have? | Eight (8).
  12. List the branches of the External Carotid Artery (ECA) (8). | 1) Superior Thyroid
    2) Ascending Pharyngeal
    3) Lingual
    4) Facial
    5) Occipital
    6) Posterior Auricular
    7) Maxillary
    8) Superficial Temporal
  13. State the mnemonic for the External Carotid Artery (ECA) branches. | "Seven Angry Ladies Fight Over PMS".
  14. What venous structure is involved in the Danger Triangle of the face? | Facial vein.
    Drains to ophthalmic vein then cavernous sinus.
  15. Why is the Danger Triangle of the face clinically significant? | Spread of infection.
    Allows infections to spread to the brain.
  16. Which areas are drained by the Submental lymph nodes? | Chin and mouth floor.
    Also drains the lower lip.
  17. Which areas are drained by the Submandibular lymph nodes? | Medial face and nose.
    Also drains the upper lip.
  18. What nerve enters the Mandibular foramen? | Inferior Alveolar Nerve.
    This is a branch of CN V3.

INITIAL ASSESSMENT

  1. List the Priorities of management in order (6). | 1) Circulation/hemorrhage
    2) Airway
    3) Shock
    4) Life-threatening associated injuries
    5) Local injuries
    6) Triage
  2. What is the first (1st) priority in Maxillofacial Trauma management? | Circulation/hemorrhage.
  3. What is the second (2nd) priority in Maxillofacial Trauma management? | Airway.
  4. List the Signs of shock in maxillofacial trauma. | Hypertension then hypotension.
    Includes tachycardia, syncope, and loss of consciousness.
  5. List the Causes of airway problems (4). | 1) Tongue falling back
    2) Dentures/clots/aspiration
    3) Laryngeal trauma
    4) Multiple facial fractures

AIRWAY MANAGEMENT

  1. What is the fastest general procedure to secure an airway? | Endotracheal Intubation.
  2. When is Endotracheal Intubation contraindicated? | Tumors or fractured mandibles.
    Specifically when the tongue cannot be elevated.
  3. Where is a Cricothyrotomy performed? | Cricothyroid ligament.
  4. Which airway procedure is the "fastest" in a field/barrio setting? | Cricothyrotomy.
    Prevents hypoxic encephalopathy.
  5. What is the preferred definitive airway in a hospital setup? | Tracheostomy.
  6. Which procedure is used for tetanus patients where ETT is impossible? | Tracheostomy.
    Used for patients with risus sardonicus.

NASAL BONE TRAUMA

  1. Which is the MOST frequently traumatized bone in the face? | Nasal bone.
    Due to its prominence.
  2. List the Signs of nasal fracture (4). | 1) Septal deviation
    2) Epistaxis
    3) Nasal obstruction
    4) Crepitation
  3. What is involved in a Plane 3 Nasal Injury? | Naso-orbitoethmoidal (NOE) and orbit.
    According to Stranc and Robertson.
  4. What is the gold standard treatment for nasal bone fractures? | Closed Reduction.
  5. Within what time frame must Closed Reduction of the nose be performed? | Within 2 weeks.
  6. When is Open Reduction and Internal Fixation (ORIF) required for the nose? | Fractures >2 weeks old.
    Required due to callus formation.
  7. What material is used for ORIF in nasal fractures? | Titanium implants.
  8. What is the primary purpose of Nasal packing? | Control bleeding.
    Can also temporarily elevate fractured bone.
  9. What is the time limit for Nasal packing removal? | 24-48 hours.
    To avoid SSI/Staphylococcal infection.

MANDIBLE TRAUMA

  1. What is the 2nd most common facial fracture? | Mandibular fractures.
  2. List the Anatomical parts of the Mandible (8). | 1) Symphysis
    2) Parasymphysis
    3) Body
    4) Angle
    5) Ramus
    6) Coronoid
    7) Condyle
    8) Alveolus
  3. Which part of the mandible is considered the midline? | Symphysis.
  4. Define the Parasymphysis of the mandible. | Midline to canine.
  5. Define the Mandibular Body region. | Canine to 3rd molar.
  6. What symptom is characteristic of Mandibular body fractures? | Lower jaw paresthesia.
    Numbness of the lower lip.
  7. Why does lower lip numbness occur in mandibular body fractures? | Inferior Alveolar Nerve compression.
    The nerve is branch V3.
  8. What are Favorable mandibular fractures? | Bone fragments stay together.
    Held by muscle forces (Masseter).
  9. What are Unfavorable mandibular fractures? | Bone fragments separate.
    Caused by muscle pull; requires ORIF.
  10. What is the most important hallmark sign in mandibular trauma? | Sublingual hematoma.
    Indicates pending upper airway obstruction.
  11. Define Trismus in terms of measurement. | Inter-incisor distance <1.5 cm.
    Normal is ~3 cm.
  12. How many finger breadths represent a normal mouth opening? | Three (3) fingers.
  13. What is Malocclusion? | Abnormal bite.
    Patient cannot bite normally.
  14. What causes Otorrhagia in mandibular trauma? | Fractured condyle.
    Pierces the external auditory canal.
  15. Which X-ray view is used for the Mandibular Condyle? | Towne’s view.
  16. Which X-ray view is used for the Mandibular Body? | Panoramic X-ray.
  17. What are Erich Braces used for? | Closed reduction.
    Locks the bite for 3-4 weeks.
  18. What is another name for Erich Braces? | Dental Arch Bars.
  19. How long are Erich Braces usually kept in place? | 3-4 weeks.
  20. What is the most important goal in managing mandibular fractures? | Restoring occlusion.
    Restoring the normal bite.

MAXILLARY TRAUMA

  1. What is a LeFort I fracture? | Horizontal palate fracture.
    Also called Guerin fracture.
  2. What is a LeFort II fracture? | Pyramidal midface fracture.
    Separates midface from cheeks.
  3. What is a LeFort III fracture? | Craniofacial dysjunction.
    Separates midface from cranium.
  4. How is Drawer’s sign performed? | Pulling the dentition.
    Checks for movement at LeFort levels.
  5. Why is Nasogastric Tube (NGT) insertion dangerous in LeFort III? | May enter the brain.

ZYCOMA TRAUMA

  1. What does ZMC Fracture stand for? | Zygomaticomaxillary Complex.
    Formerly known as Tripod fracture.
  2. How many structures are involved in a ZMC Fracture? | Six (6).
    Includes zygomaticofrontal and maxillary sutures.
  3. What does the Teardrop sign indicate? | Herniated orbital contents.
    Fat/muscle in the maxillary sinus.
  4. Which specific X-ray view shows the Teardrop sign? | Water’s view.
  5. What are the critical functional findings in ZMC fractures? | Eye motion limitation/Diplopia.
  6. Which muscle is most common in ZMC muscle entrapment? | Inferior oblique.
  7. What gaze is limited by Inferior oblique entrapment? | Upward/lateral gaze.
  8. Injury to which nerve in ZMC fractures causes cheek numbness? | Infraorbital nerve (V2).
  9. Define Hypoglobus. | Inferior orbital displacement.
    The "up/down" displacement.
  10. Define Enophthalmos. | Posterior orbital displacement.
    The "front/back" or sunken eye.
  11. List the functional indications for ORIF in ZMC (3). | 1) Limited eye motion
    2) Diplopia
    3) Trismus
  12. What separates entrapment from nerve paralysis? | Forced Duction Test.
  13. In Forced Duction Test, what does "restricted movement" mean? | Muscle entrapment.
  14. In Forced Duction Test, what does "easy movement" mean? | Nerve paralysis.

DIFFERENTIATING ENTITIES

  1. Compare Nasal vs. Mandible fracture frequency. | Nasal #1, Mandible #2.
    Nasal is most common; Mandible is 2nd.
  2. Compare Cricothyrotomy vs. Tracheostomy purpose. | Emergency vs. Definitive.
    Cricothyrotomy is temporary; Tracheostomy is hospital-based.
  3. Compare V2 vs. V3 Nerve Injury site of numbness. | Upper vs. Lower lip.
    V2 (ZMC) affects upper lip; V3 (Mandible) affects lower lip.
  4. Compare Favorable vs. Unfavorable mandible fractures. | Bone stability.
    Favorable held by muscle; Unfavorable pulled apart.
  5. Compare LeFort I vs. II vs. III levels. | Palate, Pyramidal, Face-to-Skull.
    I is palate; II is midface; III is craniofacial separation.
  6. Compare Trismus in Mandible vs. ZMC. | Displacement vs. Impingement.
    ZMC trismus involves the zygomatic arch/Coronoid Process.
  7. Compare Hypoglobus vs. Enophthalmos. | Downward vs. Sunken.
    Hypoglobus is vertical; Enophthalmos is posterior.
  8. Compare Manual reduction vs. ORIF timing in nose fractures. | 2-week threshold.
    <2 weeks for closed; >2 weeks for ORIF.
  9. Compare Submental vs. Submandibular drainage. | Chin vs. Medial Face.
    Submental drains floor of mouth/chin.
  10. Compare Lateral Pterygoid vs. Other masticatory muscles. | Open vs. Close.
    Lateral Pterygoid "Opens"; others "Close".
  11. Compare Towne’s View vs. Panoramic X-Ray. | Condyle vs. Body.
    Towne's is for Condyle; Panorex is for the body.
  12. Describe Water’s View's unique diagnostic feature. | Teardrop sign.
    Specific for orbital/ZMC fractures.
  13. Compare Functional vs. Cosmetic indications in ZMC surgery. | Diplopia vs. Enophthalmos.
    Functional is primary; Cosmetic is secondary.
  14. Compare Cricothyrotomy vs. Tracheostomy anatomy. | Ligament vs. Tracheal rings.
    Cricothyrotomy is higher (cricothyroid ligament).

MNEMONICS AND SPECIFICS

  1. What is the mnemonic for External Carotid Artery (ECA)? | "Seven Angry Ladies Fight Over PMS".
  2. What is the mnemonic for Facial Nerve (CN VII)? | "To Zanzibar By Motor Car".
  3. What is the mnemonic for Lateral Pterygoid function? | "LO - Lateral Opens".
  4. What does the "S" stand for in ECA mnemonic (1st branch)? | Superior Thyroid.
  5. What does the "A" stand for in ECA mnemonic (2nd branch)? | Ascending Pharyngeal.
  6. What does the "L" stand for in ECA mnemonic (3rd branch)? | Lingual.
  7. What does the "F" stand for in ECA mnemonic (4th branch)? | Facial.
  8. What does the "O" stand for in ECA mnemonic (5th branch)? | Occipital.
  9. What does the "P" stand for in ECA mnemonic (6th branch)? | Posterior Auricular.
  10. What does the "M" stand for in ECA mnemonic (7th branch)? | Maxillary.
  11. What does the "S" stand for in ECA mnemonic (8th branch)? | Superficial Temporal.
  12. Define the specific location for a Cricothyrotomy. | Thyroid and cricoid cartilages.
  13. What condition is Risus Sardonicus associated with? | Tetanus.
    Causes rigid jaw; necessitates Tracheostomy.

2

Summary

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THYROID DISEASES AND SURGERY

FeatureGoiterPapillary Thyroid CA (PTC)Follicular Thyroid CA (FTC)Medullary Thyroid CA (MTC)Anaplastic Thyroid CA (ATC)
PathogenesisColloid accumulation; often Hashimoto'sWell-differentiated; lymphatic spreadWell-differentiated; hematogenous spreadArises from Parafollicular C CellsPoorly differentiated; worst prognosis
CommonalityCommon in hypothyroidismMost common (60-70%)10% of thyroid cancers5% of thyroid cancers5% of thyroid cancers
DemographicsVariesF > M; 30-40 years oldF > M; ~50 years oldAssociated with MEN 2A/2BF > M; 60-70 years old
Key FindingsNontoxic/Toxic; moves with deglutitionOrphan Annie eye; Psammoma bodiesDistant mets (Lung > Liver > Brain)High Calcitonin and CEARapidly growing; aggressive
TreatmentLevothyroxine (<3cm) or Surgery (>3cm)Total Thyroidectomy ± Neck Dissection ± RAITotal Thyroidectomy ± Neck Dissection ± RAITotal Thyroidectomy + Neck DissectionPalliative only (Trach, Gastrostomy)
  • (Approach) History and PE account for 90% of diagnoses in patients presenting with a Thyroid mass.
  • (Approach) A Thyroid mass is clinically identified because it characteristically moves during deglutition (swallowing).
  • (Approach) If a neck mass does not move with deglutition, the Differential Diagnosis should include lymph nodes, esophageal masses, or schwannomas.
  • (Approach) A Thyroid panel typically includes FT3, FT4, and TSH; elevated TSH indicates hypothyroidism while decreased TSH indicates hyperthyroidism.
  • (Approach) Perform a Metastatic work-up (liver UTZ, CXR, Thyroid Body Scan) prior to operation if cancer is diagnosed.
  • (Approach) DO NOT perform FNAB if you suspect a Toxic thyroid state/Hyperthyroidism as puncturing the mass can leak hormone and exacerbate the condition.
  • (Approach) The TI-RADS (Thyroid Imaging Reporting & Data System) scale for ultrasound ranges from 1 (Benign) to 5 (Highly suspicious).
  • (Approach) The definitive diagnosis for a thyroid mass is obtained via Fine Needle Aspiration Biopsy (FNAB).
  • (Approach) According to the lecturer, FNAB becomes optional if History, PE, Thyroid Panel, and Bilateral Ultrasound are already strongly indicative of cancer.
  • (Approach) Surgery is indicated for a Thyroid mass if there is obstruction of breathing/swallowing, if it is refractory to medication, if it is malignant, or per patient choice.
  • (Approach) A Unilateral solitary nodule has a higher chance of being malignant compared to a diffusely enlarged or toxic goiter.
  • (Approach) Philippine Guidelines for Total Thyroidectomy mandate the procedure for cancerous nodules > 1 cm, whereas US Guidelines suggest > 4 cm.
  • (Approach) Filipino thyroid cancers are considered among the most aggressive types and are likely to recur, justifying more aggressive management.
  • (Goiter) Levothyroxine is used for thyroid suppression therapy in non-toxic goiters < 3 cm to provide negative feedback and reduce TSH production.
  • (Goiter) Suppression therapy/Levothyroxine for a Goiter is a preventive measure and does not typically make the existing nodule disappear.
  • (PTC) At the board exams, use Orphan Annie eye nucleus as the specific histological marker for Papillary Thyroid Carcinoma, as Psammoma bodies are only present in 40% of cases.
  • (PTC) Papillary Thyroid Carcinoma spread is primarily lymphatic, usually involving Level VI or central neck nodes.
  • (PTC) Radioactive Iodine (RAI) is indicated for Papillary Thyroid CA if the tumor is > 1 cm (PH guidelines), is an aggressive type, has lymph node metastasis, or extra-thyroidal invasion.
  • (PTC) Extra-thyroidal invasion of Papillary Thyroid Carcinoma often involves the "S-O-T-S" strap muscles: Sternohyoid, Omohyoid, Sternothyroid, and Thyrohyoid.
  • (FTC) Follicular Thyroid Carcinoma spread is primarily hematogenous, often resulting in metastases to the lungs, liver, and brain.
  • (MTC) Medullary Thyroid Carcinoma is the only thyroid CA type that does not develop in a thyroglossal duct cyst or lingual thyroid.
  • (MTC) Pre-op and post-op work-up for Medullary Thyroid Carcinoma must include monitoring levels of Calcitonin, Calcium, and CEA.
  • (MTC) If Medullary Thyroid Carcinoma is associated with Parathyroid hyperplasia, it is classified as MEN 2A; if not, it is MEN 2B.
  • (ATC) Anaplastic Thyroid Carcinoma has a mortality rate of over 90% and may transform from a long-standing papillary thyroid carcinoma.
  • (Staging) For Thyroid Cancer Staging in patients < 45 years, Stage I includes any size/local nodes, and Stage II includes distant metastases.
  • (Staging) For Thyroid Cancer Staging in patients ≥ 45 (or 55) years:
    • Stage I: ≤ 2 cm.
    • Stage II: 2-4 cm.
    • Stage III: > 4 cm (within thyroid) OR any size with spread to local tissues (not nodes).
    • Stage IV: Spread to trachea, esophagus, larynx, or distant organs.
  • (Staging) In the Thyroid N-staging, N1a refers to Level VI (central) nodes, while N1b refers to levels I-V (lateral) or superior mediastinal nodes.

SALIVARY GLAND TUMORS

FeaturePleomorphic AdenomaWarthin’s TumorMucoepidermoid CA (MEC)Acinic Cell CAAdenoid Cystic CA
NatureMost common benign (75%)2nd most common benignMost common malignantLow-grade malignantHigh-grade malignant
Unique FindingsBenign mixed tumor; lobulatedBilateral (10%); Smoker associationSquamoid vs Mucous cellsLooks like normal tissue on FNABSwiss cheese/Cribriform; Perineural invasion
DemographicsF > M; 35-50 yearsUsually males/smokersAll agesAll agesM = F; 50-60 years
ManagementSuperficial/Total ParotidectomyExcision or ParotidectomyTotal Parotidectomy + Neck DissectionParotidectomyTotal Parotidectomy + Neck Dissection + RT
  • (Salivary) The Rule of Salivary Glands states: the smaller the gland, the higher the chance of malignancy (Parotid 70% benign, Sublingual 70% malignant).
  • (Salivary) The Most common parotid tumor in the pediatric population is a Hemangioma.
  • (Pleomorphic) Pleomorphic Adenoma can transform into the aggressive "Carcinoma Ex Pleomorphic Adenoma" in 1.5% of cases within 5 years, and 10% after 15 years.
  • (Pleomorphic) The four red flags for Pleomorphic Adenoma malignancy transformation are: Facial Nerve Paralysis, Cervical Lymphadenopathy, Rapid Growth, and Involvement of the Deep Lobe.
  • (Parotid) The Facial Nerve (CN VII) passes between the superficial and deep lobes of the parotid gland.
  • (Parotid) Superficial Parotidectomy is performed if the tumor is in the superficial lobe, while Total Parotidectomy is required if the tumor involves the deep lobe to preserve nerve branches.
  • (Parotid) A Deep lobe parotid tumor may present with bulging of the lateral pharyngeal wall; bimanual palpation is used if no bulging is visible.
  • (Facial Nerve) The five branches of the Facial Nerve within the parotid are: Temporal, Zygomatic, Buccal, Marginal Mandibular, and Cervical.
  • (Facial Nerve) The Zygomatic branch is the most important as it supplies muscles for eye closure; the Cervical branch is the first that may be sacrificed.
  • (Warthin’s) Warthin’s tumor, or Papillary Cystadenoma Lymphomatosum, arises from cystic changes in parotid lymph nodes and is the only tumor that can be treated by simple excision.
  • (MEC) In Mucoepidermoid Carcinoma, a higher ratio of squamoid cells compared to mucous cells indicates a higher histological grade.
  • (Acinic) Acinic Cell Carcinoma is often mistaken for normal salivary tissue on FNAB; a second opinion or MRI/PET scan is recommended to avoid medico-legal issues.
  • (Adenoid Cystic) Adenoid Cystic Carcinoma is notorious for perineural invasion, allowing it to travel along axons to the skull base or brain.
  • (Salivary Staging) Salivary Tumor T-Staging:
    • T1: ≤ 2 cm.
    • T2: 2 - 4 cm.
    • T3: > 4 cm or extraparenchymal extension.
    • T4a: Invades skin, mandible, ear canal, or facial nerve.
    • T4b: Invades skull base, pterygoid plates, or carotid artery.
  • (Salivary Staging) Salivary Tumor N-Staging:
    • N1: Single ipsilateral ≤ 3 cm.
    • N2a: Single ipsilateral 3-6 cm.
    • N2b: Multiple ipsilateral ≤ 6 cm.
    • N2c: Bilateral/Contralateral nodes ≤ 6 cm.
    • N3: > 6 cm.
  • (Complications) Frey’s Syndrome (Gustatory Sweating) is caused by aberrant reinnervation between the auriculotemporal nerve (parasympathetic) and sweat glands (sympathetic).
  • (Complications) The Starch-iodine test (Minor test) is the diagnostic PE for Frey’s Syndrome, where a positive result (sweating while eating) turns the area bluish.
  • (Complications) Treatment for Frey's Syndrome includes anti-perspirants (Rexona), Botox, or Scopolamine ointment.
  • (Complications) Sialolithiasis is most common in the submandibular gland because its saliva is more mucoid/viscous compared to the serous saliva of the parotid.
  • (House-Brackmann) The House-Brackmann Scale grades facial nerve injury:
    • Grade I: Normal.
    • Grade II: Mild; complete eye closure with minimum effort.
    • Grade III: Moderate; complete eye closure with effort.
    • Grade IV: Moderately severe; incomplete eye closure.
    • Grade V: Severe; barely perceptible motion; incomplete eye closure.
    • Grade VI: Total paralysis.
  • (Facial Nerve) To unmask a Grade II facial nerve injury (mild lag), ask the patient to perform "beautiful eyes" (tight eye closure).

MALIGNANT TUMORS OF THE LARYNX

SubsiteAnatomical BoundaryHallmark SymptomStridor TypeNodal Spread
SupraglottisAbove vocal cordsDysphagiaInspiratoryLevels II, III, IV
GlottisTrue vocal cordsHoarsenessVariableRare
SubglottisBelow cords to cricoidDyspneaVariableLevel VI
  • (Larynx) Squamous Cell Carcinoma accounts for 85-95% of laryngeal malignancies and is primarily associated with smoking and alcohol.
  • (Larynx) High-risk HPV types 16 and 18 (and 33/35) are risk factors for laryngeal carcinoma.
  • (Larynx) Exposure to Isopropyl alcohol, mustard gas, and asbestos are specific occupational risk factors for laryngeal CA.
  • (Larynx) Any finding of a paralyzed vocal fold (vocal cord fixation) on laryngoscopy automatically indicates Stage III Carcinoma minimum.
  • (Larynx) Differential diagnosis for Stridor includes wheezing; stridor is a high-pitched sound secondary to airway obstruction.
  • (Larynx) Management of Early Laryngeal CA (Stage I-II) involves wide local excision or radiation therapy.
  • (Larynx) Management of Advanced Laryngeal CA (Stage III-IV) involves total laryngectomy combined with neck dissection and post-op radiation.
  • (Larynx) Chemotherapy has no significant role in the management of laryngeal carcinoma.
  • (Larynx) Radiation Therapy effectiveness in the larynx can be limited because the target site moves during the procedure.
  • (Larynx) In Total Laryngectomy patients, never remove the NGT as it is used for feeding while the esophagus is being repaired/healed.

NECK DISSECTION

  1. Level IA: Submental (Floor of mouth, lower lip).
  2. Level IB: Submandibular gland (Oral cavity).
  3. Level II, III, IV: Along the SCM (Oropharynx, Larynx, Thyroid).
  4. Level V: Posterior neck (Nasopharynx).
  5. Level VI: Central compartment (Thyroid, subglottic larynx).
  • (Neck Dissection) Therapeutic neck dissection is performed when neck nodes are clinically evident/positive.
  • (Neck Dissection) Elective neck dissection is performed in node-negative patients who have a > 20% risk of occult metastasis (e.g., Supraglottic CA).
  • (Neck Dissection) Radical Neck Dissection (RND) involves removal of Levels I-V plus the SCM, IJV, and CN XI.
  • (Neck Dissection) Modified Neck Dissection (MRND) involves removal of Levels I-V but preserves one or more of the three structures (SCM, IJV, CN XI).
  • (Neck Dissection) Selective Neck Dissection (SND) involves removing only a specific selection of nodal levels (e.g., Level VI for early thyroid CA).
  • (Neck Dissection) If an elective dissection reveals a positive node, the procedure must be converted to a Radical or Modified Radical Neck Dissection.
  • (Structures) The Sternocleidomastoid (SCM) is preserved to protect the carotid artery from rupture (carotid blowout) during radiation therapy.
  • (Structures) The Internal Jugular Vein (IJV) should not be removed bilaterally at once to prevent cerebral edema; the second IJV removal must wait 3 months for angiogenesis.
  • (Structures) The Spinal Accessory Nerve (CN XI) is preserved to maintain the ability to lift objects, carry items, and shrug shoulders (trapezius function).
  • (Drainage) The Thoracic Duct is located at Level IV on the left side; injury leads to a chyle leak (chylothorax).
  • (Drainage) Management of a Chyle leak involves a low-fat diet, as fatty acids worsen the leak and can lead to sepsis.

DIFFERENTIATING CONFUSING ENTITIES

  • Papillary vs. Follicular Thyroid CA: Papillary primarily spreads through lymphatics (local nodes), whereas Follicular spreads hematogenously (distant organs like bone/liver).
  • Thyroid Node Staging vs. Other Head/Neck Staging: Thyroid N-staging is based on location (N1a central vs. N1b lateral), while Head and Neck N-staging is based on size/count (N1 <3cm, N2 3-6cm, N3 >6cm).
  • MEN 2A vs. MEN 2B: Both involve Medullary Thyroid CA, but MEN 2A includes parathyroid hyperplasia, and 2B does not.
  • Supraglottic vs. Glottic vs. Subglottic: Supraglottic = Dysphagia (swallowing), Glottic = Hoarseness (voice), Subglottic = Dyspnea (breathing).
  • Pleomorphic Adenoma vs. Warthin's Tumor: Pleomorphic is the most common and is "mixed" (solid/lobulated); Warthin's is cystic and frequently bilateral/associated with smokers.
  • Radical vs. Modified vs. Selective Neck Dissection: Radical removes 3 specific structures (SCM/IJV/CN XI); Modified saves them; Selective removes only specific levels (1-3 levels).
  • House-Brackmann Grade III vs. Grade IV: Grade III has complete eye closure with effort; Grade IV has incomplete eye closure.
  • Elective vs. Therapeutic Neck Dissection: Elective is for clinically negative (N0) necks with high risk; Therapeutic is for clinically positive (N+) nodes.
  • Thyroid vs. Salivary Staging (T2): For Thyroid, T2 is 2-4 cm; For Salivary, T2 is ≥2 cm to ≤4 cm. Both are identical in size range, but Thyroid Stage III starts > 4cm within the gland.
  • Submandibular vs. Parotid Salivation: Submandibular produces mucoid saliva (common for stones); Parotid produces serous saliva (active during eating).
  • Sublingual vs. Parotid Malignancy Rate: A sublingual mass is 70% likely to be malignant, whereas a parotid mass is 70% likely to be benign.
  • Planned vs. Salvage Neck Dissection: Planned is done regardless of response to radiation; Salvage is done for residual or persistent nodes that failed to resolve.
  • N2b vs. N2c Neck Nodes: N2b is multiple nodes on the same side (ipsilateral); N2c is nodes on both sides (bilateral) or the opposite side (contralateral).
  • Inspiratory vs. Expiratory Stridor: Inspiratory stridor usually points to a supraglottic obstruction; expiratory stridor must be differentiated from wheezing.
  • Filipino thyroid CA vs. Western Guidelines: PH surgeons perform total thyroidectomy at > 1 cm due to higher aggressiveness; Western surgeons often perform lobectomy up to 4 cm.

QA

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  1. Percentage of Thyroid mass diagnoses accounted for by History and Physical Examination? | 90%
  2. Clinical characteristic used to identify a Thyroid mass during Physical Examination? | Moves with deglutition (swallowing)
  3. Differential Diagnosis for a Neck mass that does not move with deglutition? (3) | 1) Lymph nodes
    2) Esophageal masses
    3) Schwannomas
  4. Components typically included in a Thyroid panel? (3) | FT3, FT4, and TSH
  5. Interpretation of Thyroid panel results? | Elevated TSH: Hypothyroidism;
    Decreased TSH: Hyperthyroidism
  6. Required Metastatic work-up tests prior to operation if cancer is diagnosed? (3) | Liver UTZ, CXR, Thyroid Body Scan
  7. Why must you NOT perform FNAB in a Toxic thyroid state/Hyperthyroidism? | Can leak hormone and exacerbate condition
  8. Range of the TI-RADS scale for thyroid ultrasound? | 1 (Benign) to 5 (Highly suspicious)
  9. What is the definitive diagnosis for a Thyroid mass? | Fine Needle Aspiration Biopsy (FNAB)
  10. When does FNAB become optional according to the lecturer? | If History, PE, Panel, and Ultrasound strongly indicate cancer
  11. Surgical indications for a Thyroid mass? (4) | 1) Obstruction
    2) Refractory to medication
    3) Malignant
    4) Patient choice
  12. Malignancy risk of a Unilateral solitary nodule compared to toxic goiter? | Higher chance of being malignant
  13. Philippine vs. US Guidelines for Total Thyroidectomy regarding nodule size? | PH: > 1 cm;
    US: > 4 cm
  14. Why is aggressive management justified for Filipino thyroid cancers? | Most aggressive types/likely to recur
  15. Pathogenesis of a Goiter? | Colloid accumulation; often Hashimoto's
  16. Treatment for a Goiter < 3 cm? | Levothyroxine (Suppression therapy)
  17. Pathogenesis and spread of Papillary Thyroid Carcinoma (PTC)? | Well-differentiated; lymphatic spread
  18. Most common thyroid cancer? | Papillary Thyroid Carcinoma (PTC) (60-70%)
  19. Demographics of Papillary Thyroid Carcinoma (PTC)? | Females > Males; 30-40 years old
  20. Treatment for Papillary Thyroid Carcinoma (PTC)? | Total Thyroidectomy ± Neck Dissection ± RAI
  21. Pathogenesis and spread of Follicular Thyroid Carcinoma (FTC)? | Well-differentiated; hematogenous spread
  22. Key findings in Follicular Thyroid Carcinoma (FTC)? | Distant metastases (Lung > Liver > Brain)
  23. Origin of Medullary Thyroid Carcinoma (MTC)? | Parafollicular C Cells
  24. Laboratory markers elevated in Medullary Thyroid Carcinoma (MTC)? | Calcitonin and CEA
  25. Nature and prognosis of Anaplastic Thyroid Carcinoma (ATC)? | Poorly differentiated; worst prognosis
  26. Demographics of Anaplastic Thyroid Carcinoma (ATC)? | Females > Males; 60-70 years old
  27. Palliative management for Anaplastic Thyroid Carcinoma (ATC)? | Tracheostomy and Gastrostomy
  28. Role of Levothyroxine in non-toxic goiters < 3 cm? | Provides negative feedback; reduce TSH production
  29. Does suppression therapy for a Goiter make existing nodules disappear? | No; it is preventive
  30. Specific histological marker for Papillary Thyroid Carcinoma (PTC) at board exams? | Orphan Annie eye nucleus
  31. Primary spread of Papillary Thyroid Carcinoma (PTC)? | Lymphatic (Level VI/central nodes)
  32. Indications for Radioactive Iodine (RAI) in PTC? (4) | 1) >1 cm (PH)
    2) Aggressive type
    3) Node metastasis
    4) Extra-thyroidal invasion
  33. Muscles involved in "S-O-T-S" extra-thyroidal invasion of PTC? (4) | Sternohyoid, Omohyoid, Sternothyroid, Thyrohyoid
  34. Primary spread of Follicular Thyroid Carcinoma (FTC)? | Hematogenous
  35. Which thyroid cancer does NOT develop in a thyroglossal duct cyst? | Medullary Thyroid Carcinoma (MTC)
  36. Pre-op and post-op work-up for Medullary Thyroid Carcinoma (MTC)? (3) | Calcitonin, Calcium, and CEA
  37. Classification of Medullary Thyroid Carcinoma with Parathyroid hyperplasia? | MEN 2A
  38. Classification of Medullary Thyroid Carcinoma without Parathyroid hyperplasia? | MEN 2B
  39. Mortality rate of Anaplastic Thyroid Carcinoma (ATC)? | Over 90%
  40. Thyroid Cancer Staging (Patient < 45 years) for Stage I? | Any size / local nodes
  41. Thyroid Cancer Staging (Patient < 45 years) for Stage II? | Distant metastases
  42. Thyroid Cancer Staging (Patient ≥ 45 years) for Stage I? | ≤ 2 cm
  43. Thyroid Cancer Staging (Patient ≥ 45 years) for Stage II? | 2 - 4 cm
  44. Thyroid Cancer Staging (Patient ≥ 45 years) for Stage III? | > 4 cm (intra-thyroid) OR local tissue spread (not nodes)
  45. Thyroid Cancer Staging (Patient ≥ 45 years) for Stage IV? | Spread to trachea, esophagus, larynx, or distant organs
  46. Thyroid N-staging: definition of N1a? | Level VI (central) nodes
  47. Thyroid N-staging: definition of N1b? | Levels I-V (lateral) or superior mediastinal nodes
  48. Most common benign salivary tumor? | Pleomorphic Adenoma (75%)
  49. Most common malignant salivary tumor? | Mucoepidermoid Carcinoma (MEC)
  50. Unique findings for Warthin’s Tumor? (2) | 1) Bilateral (10%)
    2) Smoker association
  51. Key histological finding in Adenoid Cystic Carcinoma? | Swiss cheese (Cribriform) appearance
  52. Nature of spread in Adenoid Cystic Carcinoma? | Perineural invasion
  53. Management for Acinic Cell Carcinoma? | Parotidectomy
  54. Definition of Rule of Salivary Glands? | Smaller gland = Higher chance of malignancy
  55. Malignancy rates of Parotid vs. Sublingual glands? | Parotid: 70% benign;
    Sublingual: 70% malignant
  56. Most common parotid tumor in the Pediatric population? | Hemangioma
  57. Transformation rate of Pleomorphic Adenoma after 15 years? | 10% (to Carcinoma Ex Pleomorphic Adenoma)
  58. Four red flags for Pleomorphic Adenoma malignancy? | 1) Nerve Paralysis
    2) Lymphadenopathy
    3) Rapid Growth
    4) Deep Lobe involvement
  59. Anatomical location of the Facial Nerve (CN VII) in the parotid? | Between superficial and deep lobes
  60. Indication for Total Parotidectomy regarding lobe involvement? | Tumor involving the deep lobe
  61. Presentation of a Deep lobe parotid tumor on physical exam? | Bulging of lateral pharyngeal wall
  62. Five branches of the Facial Nerve in the parotid? | Temporal, Zygomatic, Buccal, Marginal Mandibular, Cervical
  63. Most important Facial Nerve branch for eye closure? | Zygomatic branch
  64. Another name for Warthin’s Tumor? | Papillary Cystadenoma Lymphomatosum
  65. Histological grading criteria for Mucoepidermoid Carcinoma? | Higher ratio of squamoid cells to mucous cells
  66. Why is Acinic Cell Carcinoma often mistaken for normal tissue on FNAB? | Looks like normal salivary tissue
  67. Route of travel for Adenoid Cystic Carcinoma to the skull base? | Along axons (Perineural invasion)
  68. Salivary Tumor T-Staging: T1 vs T2 size? | T1: ≤ 2 cm;
    T2: 2 - 4 cm
  69. Salivary Tumor T-Staging: T4a involvement? (4) | Skin, mandible, ear canal, or facial nerve
  70. Salivary Tumor N-Staging: N1 definition? | Single ipsilateral ≤ 3 cm
  71. Salivary Tumor N-Staging: N2c definition? | Bilateral or Contralateral nodes ≤ 6 cm
  72. Cause of Frey’s Syndrome (Gustatory Sweating)? | Aberrant reinnervation (parasympathetic to sympathetic)
  73. Diagnostic test for Frey’s Syndrome? | Starch-iodine test (Minor test)
  74. Treatments for Frey's Syndrome? (3) | anti-perspirants, Botox, or Scopolamine
  75. Most common site for Sialolithiasis and why? | Submandibular gland (Viscous/mucoid saliva)
  76. House-Brackmann Grade III description? | Moderate; complete eye closure with effort
  77. House-Brackmann Grade IV description? | Moderately severe; incomplete eye closure
  78. Physical exam maneuver to unmask Grade II facial nerve injury? | Ask for "beautiful eyes" (tight eye closure)
  79. Hallmark symptom and stridor type for Supraglottis tumors? | Dysphagia; Inspiratory stridor
  80. Hallmark symptom and nodal spread for Glottis tumors? | Hoarseness; Rare spread
  81. Hallmark symptom and nodal spread for Subglottis tumors? | Dyspnea; Level VI spread
  82. Most common histological type of Laryngeal malignancy? | Squamous Cell Carcinoma (85-95%)
  83. High-risk HPV types associated with laryngeal carcinoma? | Types 16 and 18
  84. Occupational risk factors for Laryngeal CA? (3) | Isopropyl alcohol, mustard gas, and asbestos
  85. Minimum staging for Laryngeal Carcinoma with vocal cord fixation? | Stage III
  86. Definintion of Stridor? | High-pitched sound secondary to airway obstruction
  87. Management of Early Laryngeal CA (Stage I-II)? | Wide local excision or radiation therapy
  88. Management of Advanced Laryngeal CA (Stage III-IV)? | Total laryngectomy + neck dissection + post-op radiation
  89. Role of Chemotherapy in laryngeal carcinoma? | No significant role
  90. Why is Radiation Therapy effectiveness limited in the larynx? | Target site moves during procedure
  91. Why must the NGT never be removed in Total Laryngectomy patients? | Feeding while esophagus heals
  92. Anatomical site for Level IA Neck Dissection? | Submental (Floor of mouth, lower lip)
  93. Anatomical site for Level IB Neck Dissection? | Submandibular gland (Oral cavity)
  94. Anatomical site for Level II, III, IV Neck Dissection? | Along the SCM (Oropharynx, Larynx, Thyroid)
  95. Anatomical site for Level V Neck Dissection? | Posterior neck (Nasopharynx)
  96. Anatomical site for Level VI Neck Dissection? | Central compartment (Thyroid, subglottic larynx)
  97. Definition of Therapeutic neck dissection? | Performed when nodes are clinically evident/positive
  98. Definition of Elective neck dissection? | Performed in N0 patients with >20% occult risk
  99. Structures removed in Radical Neck Dissection (RND)? | Levels I-V, SCM, IJV, and CN XI
  100. Definition of Modified Neck Dissection (MRND)? | Levels I-V removed; preserves SCM, IJV, or CN XI
  101. Definition of Selective Neck Dissection (SND)? | Removal of specific nodal levels only
  102. Action required if Elective neck dissection reveals positive nodes? | Convert to Radical or Modified Radical
  103. Reason for preserving the Sternocleidomastoid (SCM)? | Protect carotid artery from blowout/rupture
  104. Precaution for Internal Jugular Vein (IJV) bilateral removal? | Wait 3 months for second IJV removal (prevents cerebral edema)
  105. Function maintained by preserving Spinal Accessory Nerve (CN XI)? | Shoulder shrugging (trapezius function)
  106. Location and consequence of injury to the Thoracic Duct? | Level IV (left side); results in chyle leak
  107. Management of a Chyle leak after neck surgery? | Low-fat diet
  108. Compare spread of Papillary vs. Follicular Thyroid CA. | Papillary: Lymphatic;
    Follicular: Hematogenous
  109. Basis of Thyroid Node Staging vs. Head/Neck Staging? | Thyroid: Location;
    Head/Neck: Size and Count
  110. Difference between MEN 2A vs. MEN 2B? | 2A has parathyroid hyperplasia; 2B does not
  111. Compare hallmark symptoms: Supraglottic vs Glottic vs Subglottic. | Supraglottic: Dysphagia;
    Glottic: Hoarseness;
    Subglottic: Dyspnea
  112. Compare Pleomorphic Adenoma vs. Warthin's Tumor nature. | Pleomorphic: Most common/Mixed;
    Warthin's: Cystic/Bilateral/Smokers
  113. Difference between N2b vs. N2c neck nodes? | N2b: Multiple ipsilateral;
    N2c: Bilateral or Contralateral
  114. Difference between Planned vs. Salvage neck dissection? | Planned: Regardless of response;
    Salvage: For residual/persistent disease
  115. Size range for T2 staging in both Thyroid and Salivary? | 2 - 4 cm

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Summary

QA